Alan D. D'Andrea, M.D.
Professor, Harvard Medical School
Alan D’Andrea, M.D. is the Fuller-American Cancer Society Professor of Medicine at Harvard Medical School and the Director of the Center for DNA Damage and Repair at the Dana-Farber Cancer Institute in Boston. His research is focused on the identification of genetic vulnerabilities in human cancers including leukemia, ovarian, and breast cancer. Dr. D’Andrea is a member of the Board of Scientific Counselors of the National Cancer Institute and is a recipient of the G.H.A. Clowes Award from the American Association of Cancer Research. He currently co-leads the Stand up to Cancer Ovarian Cancer Dream Team with Dr. Elizabeth Swisher.
Trey Ideker, Ph.D.
Professor, University California at San Diego
Trey Ideker, Ph.D., is a Professor in Medicine, Bioengineering and Computer Science at UCSD; Co-Director of the Cancer Genomes and Networks Program at UCSD Moores Comprehensive Cancer Center, and Director of the San Diego Center for Systems Biology. His lab develops technology to build molecular network maps of the cell and to use these networks to translate genotype to phenotype in cancer. He has founded influential bioinformatic tools including Cytoscape, a popular network analysis platform which has been cited >12,000 times. Ideker serves on the Editorial Boards for Cell, Cell Reports, Molecular Systems Biology, and PLoS Computational Biology and is a Fellow of AAAS and AIMBE. He was named one of the Top 10 Innovators of 2006 by Technology Review magazine and was the recipient of the 2009 Overton Prize from the International Society for Computational Biology.
Stephen Kowalczykowski, Ph.D.
Professor, University of California at Davis
Member, National Academy of Sciences
Stephen Kowalczykowski, Ph.D., is a Distinguished Professor of Microbiology and Molecular Genetics, and of Molecular and Cell Biology at the University of California at Davis. He received his Ph.D. in chemistry and biochemistry with Dr. Jacinto Steinhardt at Georgetown University. His postdoctoral training was with Dr. Peter von Hippel at the University of Oregon. Dr. Kowalczykowski started his independent faculty career in 1981 at Northwestern University Medical School. In 1991, he relocated to the University of California at Davis with the rank of Full Professor. He subsequently served as the Chair of Microbiology and the Director of the Center for Genetics and Development. Dr. Kowalczykowski’s honors include election to the National Academy of Sciences (2007), the American Academy of Arts and Sciences (2005), the American Academy of Microbiology (2003), and the American Association for the Advancement of Science (2001). Dr. Kowalczykowski’s research programs focus on the molecular mechanisms of recombinational DNA repair; the function of homologous recombination in the maintenance of genomic integrity.
John Petrini, Ph.D.
Member, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center
John Petrini, Ph.D., is a Member in the Molecular Biology Program of the Sloan Kettering Institute at the Memorial Sloan Kettering Cancer Center in New York, and the founding Director of the Functional Genomics Initiative at MSKCC. Dr. Petrini received his Ph.D. in 1988 from the University of Michigan Medical School, Ann Arbor, MI, and conducted postdoctoral work at the Dana Farber Cancer Institute at the Harvard Medical School. He began his independent research career at the University of Wisconsin in 1994, and was recruited to MSKCC in 2002. The work in Dr. Petrini's lab is focused on the DNA damage response, a network of functions comprising DNA damage signaling, DNA repair, and DNA damage dependent cell cycle regulation. His laboratory employs yeast and mice to undertake genetic, molecular biological, and biochemical analyses of the pathways in eukaryotic cells that are responsive to chromosome breaks.
Elizabeth Swisher, M.D.
Professor, University of Washington
Elizabeth Swisher, M.D., is a gynecologic oncologist, Professor of Gynecologic Oncology, and adjunct Professor of Medical Genetics at the University of Washington in Seattle. Dr. Swisher’s research focused on understanding the role of the BRCA-Fanconi anemia pathway in ovarian cancer and how defects in DNA repair can be exploited in the therapy and prevention of ovarian carcinoma. She is co-Leader of Stand up to Cancer’s first Ovarian Cancer Dream Team. She is principal investigator on several PARP inhibitor therapeutic trials and collaborates on the translational research for numerous other clinical trials in ovarian and other cancers.
Lawrence Fong, M.D.
Co-Leader, Cancer Immunotherapy Program, and Efim Guzik Distinguished Professor in Cancer Biology at UCSF
Chris Goodnow, Ph.D.
Deputy Director, The Garvan Institute of Medical Research
Member, National Academy of Sciences
Chris Goodnow, Ph.D. is the Bill and Patricia Ritchie Foundation Chair and is NHMRC Australia Fellow, Head of the Immunogenomics lab and Deputy Director at the Garvan Institute of Medical Research in Sydney, Australia. He trained in veterinary medicine and surgery, immunochemistry, and immunology at the University of Sydney and in molecular biology at Stanford University. After doctoral studies begun at the Walter and Eliza Hall Institute in Melbourne and performed at Sydney University, he joined the faculty of Stanford University Medical School and the Howard Hughes Medical Institute in 1990. To pioneer large-scale genetic analysis of the immune system, he joined the faculty at the Australian National University in 1997 as Professor and Director of the Medical Genome Centre, leading its development into a Major National Research Facility, the Australian Phenomics Facility. He is also President of the Australasian Society for Immunology 2015-2016. His research contributions have been recognised by a number of awards, including American Association of Immunologists (AAI) Pharmingen Investigator Award, AAI Distinguished Lecturer, Australasian Society for Immunology Burnet Orator, Gottschalk Medal, Health Minister’s Prize, Centenary Medal, Ramaciotti Medal, GSK Award for Research Excellence, Fellow of the Australian Academy of Science, Fellow of the Royal Society, and Member of the US National Academy of Sciences.
Richard J. Ulevitch, Ph.D.
Scripps Research Institute, Chairman Emeritus, Department of Immunology
Venture Partner, 5AM Ventures
Richard J. Ulevitch, Ph.D., joined 5AM Ventures in February 2008 as a Venture Partner. Previously he was Chairman of 5AM’s Scientific Advisory Board while serving as Professor and Chairman of the Department of Immunology at The Scripps Research Institute in La Jolla, California. He remains as Professor and Chairman Emeritus at The Scripps Research Institute. For nearly three decades, Dr. Ulevitch has performed research to understand the role of the immune system in human disease. He serves as a scientific advisor to Aravis Ventures, a European life science venture capital fund and previously served as an advisor to the Lombard Odier Immunology Fund, where he evaluated numerous biotechnology companies over a fifteen-year span. Dr. Ulevitch serves or has served on the Scientific Advisory Boards of Arvinas, Biodesy, Bird Rock Bio, Cidara (NASDAQ: CDTX), Cleave, Envoy (acquired by Takeda), Ideaya, Igenica, Ikaria (acquired by Mallinckrodt), Pulmatrix (NASDAQ: PULM) as well as on the Board of PhaseRx. Dr. Ulevitch received an A.B. from Washington and Jefferson College and a Ph.D. in Biochemistry from the University of Pennsylvania. Dr. Ulevitch is based in the Menlo Park, CA office.
Paul J. Reider, Ph.D.
Faculty, Princeton University
Paul J. Reider, Ph.D., joined the faculty of Princeton University in 2008 where his research isfocused on new drugs for malaria, TB and other neglected diseases. During his 28 years in the pharmaceutical industry he has directly contributed to the discovery, identification, development or registration of 14 approved drugs. From 2002-2007 he was at Amgen as Worldwide Head of Chemistry Research & Discovery. He received his A.B. (Psychology) at New York University and his Ph.D. (Organic Chemistry) at the University of Vermont. After post-doctoral research as an NIH National Research Service Awardee at Colorado State University, Paul joined Merck as a Senior Research Chemist in Process Chemistry where he remained for 22 years. Prior to joining Amgen, he was Vice President of Process Chemistry at Merck. Paul is the winner of numerous awards, most recently, he was named the winner of the 2011 National Academy of Sciences’ Award for Chemistry in Service to Society. He has served on the visiting committees for Harvard University, California Institute of Technology, and the University of California, Santa Barbara, and on the Editorial Advisory Boards of the Journal of the American Chemical Society, the Journal of Organic Chemistry, and Organic Letters. He is also a Senior Editor of Current Opinion in Drug Discovery & Development, and Science of Synthesis. In 2011, Paul joined the Scientific Advisory Boards of the Medicines for Malaria Venture and the TB Alliance.
Laura Shawver, Ph.D.
CEO, Cleave Biosciences
Laura Shawver, Ph.D., is an experienced Biotech executive with more than 25 years of experience in the development of small molecule drugs for cancer and other diseases. Prior to joining Cleave Biosciences as Chief Executive Officer and driving the $54M Series A financing, she was an Entrepreneur in Residence for 5AM Ventures beginning October 2010. From 2002 - 2010, Dr. Shawver was the Chief Executive Officer of Phenomix Corporation where she also served on the Board of Directors. Previously, Dr. Shawver was the President of SUGEN Inc. from 2000 after holding various positions since 1992. SUGEN focused on understanding key molecular pathways of cancer cells and developed the drugs Sutent™ and Palladia™. The company was acquired by Pharmacia in 1999. Prior to SUGEN, she was employed at Berlex Biosciences. She is an active member of the American Association for Cancer Research and also a member of American Society for Clinical Oncologists. Dr. Shawver is the Founder of The Clearity Foundation, a nonprofit organization providing access to molecular profiling for ovarian cancer patients to improve their treatment options. Shawver received her PhD in Pharmacology and a BS degree in Microbiology, both from the University of Iowa.